2010 Lexus RX 350 Review
Price Range: $8,121 - $17,590





+90
Edmunds' Expert Review
by the Edmunds Experts
Pros
- Premium cabin appointments, plush ride, composed handling, energetic acceleration, comfortable seating front and rear, user-friendly multifunction controller.
Cons
- No third-seat option, expensive options packages, not as entertaining to drive as sportier rivals.
What’s new
The 2010 Lexus RX 350 has been completely redesigned.
Edmunds says
Although competitors offer superior driving dynamics, the 2010 Lexus RX 350 will impress luxury crossover SUV shoppers who value plush ride quality, exceptional fit and finish, and ample day-to-day utility.
For sale near Aurora, CO
18 listings
- $9,000good price$872 below market
- 179,515 miles
- No accidents, 3 owners, personal use only
- 6cyl automatic
- Larry H. Miller Ford Lakewood (17 mi away)
- Home delivery*
- AWD/4WD
- Bluetooth
- Power Driver Seat
- Tire Pressure Warnin...
- Multi-Zone Climate C...
Close
Located in Lakewood, CO
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: Yes
Features and Specs:
20 Combined MPG (18 City/24 Highway)
Listing Information:
VIN: 2T2BK1BA7AC040934
Stock: SLL250255B
Certified Pre-Owned: No
Listed since: 02-24-2025 - $12,480fair price$91 above market
- 122,234 miles
- No accidents, 2 owners, personal use
- 6cyl automatic
- McDonald Mazda West (16 mi away)
- Home delivery*
- AWD/4WD
- Bluetooth
- Power Driver Seat
- Tire Pressure Warnin...
- Multi-Zone Climate C...
Close
Located in Lakewood, CO
2010 Lexus RX 350 ** 3.5L 6-Cylinder DOHC VVT-i 24V ** 6-Speed Automatic with Sequential Shift ECT-i ** AWD ** Golden Almond Metallic ** Parchment...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
20 Combined MPG (18 City/24 Highway)
Listing Information:
VIN: 2T2BK1BA1AC062783
Stock: WTAC062783
Certified Pre-Owned: No
Listed since: 04-21-2025
Vehicle overview
Since its inception in 1990, Lexus has made a habit of producing quality vehicles that appeal to multitudes of luxury-segment buyers. A great example is the ever-popular RX-series luxury crossover SUV. Fully redesigned for 2010, the Lexus RX 350 doesn't stray too far from its successful formula of pleasant driving dynamics, a "just right" five-passenger size, a cabin full of luxury features and impeccable build quality.
Understandably, Lexus took a conservative approach when it reworked its bread-and-butter crossover. The tweaks made to this new-generation RX include a slight increase in width (though other dimensions remain essentially unchanged), bigger standard wheels (18s versus 17s), bigger brakes, a new six-speed transmission, more airbags (now at 10), a keyless ignition system and a new mouse-like multifunction controller for the navigation system that's actually both clever and intuitive to use. One downside to these new features, however, is that they contribute to the new 2010 RX 350's weight gain -- it's up more than 400 pounds compared to last year's model.
However, you won't need to e-mail the "Biggest Loser" to ask if they have a vehicular-themed show coming up -- the increased poundage hasn't marred the 2010 RX 350's performance. If anything, we've found the new RX to be more athletic than the outgoing model, thanks to sharpened steering and a revamped suspension. A new double-wishbone rear suspension setup not only improves handling but provides a little more cargo space behind the seats, thanks to its more compact design.
Compared to its competition, the 2010 Lexus RX 350 still serves as a fine example of what a luxury crossover SUV should be. Yes, those looking for sportier corner-carving machines would still be better served by the Acura MDX, BMW X5 and Infiniti FX35. And those needing third-row accommodations should check out the Cadillac SRX, Mercedes-Benz R350 or Volvo XC90. However, if you're interested in a plush, convenience-laden five-passenger crossover, it doesn't get much better than the RX 350.
Performance & mpg
A 3.5-liter V6 rated at 275 horsepower and 257 pound-feet of torque powers the 2010 Lexus RX 350. A six-speed automatic transmission is standard, and buyers have a choice of either front-wheel drive or all-wheel drive. Lexus claims either version will run from zero to 60 mph in about 7.5 seconds.
Fuel economy estimates stand at 18 mpg city/25 mpg highway and 21 mpg combined for the FWD model, with the AWD version rating 1 mpg less. Properly equipped, the RX 350 can tow up to 3,500 pounds.
Safety
The RX 350 comes standard with no fewer than 10 airbags, which include front- and rear-seat side airbags, full-length side curtain airbags and dual front knee bags. Standard stability and traction control systems as well as antilock brakes with brake assist are on hand to help one avoid an accident in the first place.
Driving
In true Lexus fashion, the 2010 Lexus RX 350 possesses a smooth and sophisticated personality. Acceleration is swift and silent, thanks to the 3.5-liter V6 and quiet cabin. This is first and foremost a luxury vehicle, and as such, the standard suspension is tuned more for a plush ride than sporty handling, though it never feels the least bit floaty. Those seeking a firmer dynamic should consider the Sport package, which includes a sport-tuned suspension along with 19-inch wheels fitted with performance tires. Even fitted with the latter, however, the refined RX 350 still leans more toward an isolated ride than an enthusiast-oriented, involving drive.
Interior
Although the RX 350 is an entry-level luxury SUV, the cabin gives the impression that this could be the company's flagship. Real wood and high-quality leather trim make for a rich ambience, and the optional Mark Levinson sound system rivals the best systems available anywhere. In addition to voice command capability, the optional navigation system employs Remote Touch, a new interface that replaces the former touchscreen setup with a mouse-like controller located on the center console. Remote Touch is immediately intuitive and generally easier to use than interfaces offered by the RX 350's competitors.
Rear passengers will be quite comfortable thanks to the seat's reclining and sliding adjustments. That seat is split 40/20/40 to optimize both passenger comfort and cargo-carrying flexibility. When it's time to turn this luxury cruiser into a beast of burden, the RX 350 is ready with 40 cubic feet of cargo capacity with the rear seats up and 80 cubes with those seats down.
2010 Lexus RX 350 models
The 2010 Lexus RX 350 is a midsize luxury crossover SUV that seats five. Standard features include 18-inch alloy wheels, keyless ignition and entry, 10-way power front seats, a power tilt and telescoping steering wheel, wood interior trim, dual-zone automatic climate control, Bluetooth, a nine-speaker stereo (with a CD changer, steering-wheel-mounted controls and an auxiliary audio jack) and second-row seats that slide and recline.
Options include a number of packages. The Sport package adds 19-inch wheels, a sport-tuned suspension and Lexus' Vehicle Dynamics Integrated Management (VDIM) system. The Premium package adds leather seating, a sunroof, a power rear liftgate, driver seat memory settings, an auto-dimming rearview mirror and an iPod input/interface. Selecting this package allows further upgrades via the Comfort package (heated and ventilated front seats, bi-xenon adaptive headlights and rain-sensing wipers) and the Luxury package (19-inch wheels, retractable outside mirrors, upgraded leather seating, a side-monitoring system, a wood and leather steering wheel, extendable front seat cushions). The Navigation package (requires the Premium package) includes a hard-drive-based navigation system with real-time traffic, a back-up camera, Bluetooth and upgraded speakers.
Individual options include park assist, a premium Mark Levinson surround-sound audio system, a dual-rear-screen DVD entertainment system, a head-up display and the Pre-Collision System (which primes the brakes and tightens the seatbelts if a collision is deemed imminent). Many of the various package features are also available à la carte.

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Cost to DriveCost to drive estimates for the 2010 Lexus RX 350 4dr SUV (3.5L 6cyl 6A) and comparison vehicles are based on 15,000 miles per year (with a mix of 55% city and 45% highway driving) and energy estimates of $3.81 per gallon for premium unleaded in Colorado.
Monthly estimates based on costs in Colorado
$225/mo for RX 350 Base
RX 350 Base
vs
$170/mo
Avg. Midsize SUV
See Edmunds pricing data
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Reliability Ratings by RepairPal
4.5 out of 5 stars4.5/5Excellent
#3 out of 29 among Luxury Midsize SUVs
RepairPal Reliability Ratings are based on the actual cost, frequency, and severity of unscheduled repairs and maintenance on make/model data for select 2008-2022 vehicles. The reliability of a specific vehicle may vary depending on its maintenance and driving history, model year, trim, and features.
Cost
The average total annual cost for unscheduled repairs and maintenance across all model years of the Lexus RX 350 from 2008-2022.$408/yr
vs. $602/yr
for Average Luxury Midsize SUV
for Average Luxury Midsize SUV
Frequency
The average number of times this model is brought into the shop for unscheduled repairs and maintenance in a single year. RepairPal calculates this metric by tracking millions of unique vehicles over multiple years to determine an average number of visits per year (omitting small routine visits, e.g., oil changes).0.84x/yr
vs. 1.09x/yr
for Average Luxury Midsize SUV
for Average Luxury Midsize SUV
Severity
The probability that a repair will be a major issue, meaning the repair costs 3x the average annual repair cost for all models. This threshold will be higher for vehicles that have higher labor rates and parts costs (such as a premium brand).6.5%
vs. 9.4%
for Average Luxury Midsize SUV
for Average Luxury Midsize SUV
powered by RepairPal Based on RepairPal reliability data as of 8/23/2023. Ratings are provided by RepairPal and Edmunds is not responsible for their accuracy.
Lexus RX 350 Reviews
Owner Reviews
5(58%)
4(28%)
3(10%)
2(3%)
1(1%)
Most Helpful Owner Reviews
Trending topics
T’was a wonderful vehicle!
5 out of 5 starsMark, 02/01/2018
2010 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 6A)
I loved my 2010 RX350, but recently traded in for a 2017 RX350 solely because I’m (according to my wife) spoiled. It had 123,480 miles on it an rode and drove like it was new. No mechanical problems, no squeaks or rattles, nothing. (Heck, when I traded my 2004 RX 350 for the 2010 it was just as good). My only gripe about the 2010 was there was no overhead place to secure sunglasses … and the location of the USB and other charging ports (cigarette lighter style plug in) was very awkward (in the inside BOTTOM of the console).
Love the Rx 350
5 out of 5 starsjennyrn, 02/01/2013
2010 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 6A)
I have driven the Lexus RX series for over seven years now. I will never drive another car again. It has to be the smoothest ride that a car can deliever. The luxurious feel it provides and it is so spacious that you never feel smooshed no matter if you have a full car load or just two people. Everybody who drives my car always states how nice it is to drive and it is not the least bit … bumpy. I highly recommend the Lexus RX series to anybody. It never disappoints. I bought this one at the Lexus in Watertown. I will say it started out as a rough transaction but they have gone above and beyond to make the customer happy. I would recommend them, especially Steve. Very helpful and considerate.
Fine Product
4.88 out of 5 starsDon, 08/13/2010
2010 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 6A)
We purchased the 2010 RX350 as a replacement for a Volvo XC Wagon, which was a maintenance disaster. We've had one previous Lexus. I concur with many who state they don't understand the negative comments. There is little I find fault with in this vehicle. The seats are firm, comfortable on long rides, and cooled. The handling is solid, with excellent steering response. Quality … throughout exceeded what I noticed in BMW and Acura SUVs. As for gas mileage, given engine size and performance, I'm pleased, averaging 22.5 after 10,000 miles. We did not opt for the nav system, as I couldn't justify the added cost over a plug-in GPS.
Flawless used car
5 out of 5 starsBill5, 01/23/2018
2010 Lexus RX 350 4dr SUV AWD (3.5L 6cyl 6A)
I bought this car used with 25 K on the odometer. It was a dealer loaner. I now have 75 K on the odo, and it has only been back to the dealer once, for my putting an aftermarket battery in the key fob. The car is flawless. Only maintenance aside from oil changes every 5 K was brakes at 70 K. The car will be 8 years old in June, and the leather seats are showing their age. Tires … don't make it to 40 K. It is just so - so in the snow. It is sneaky fast, and very quite. It rides as solid as the first day I bought it. This car isn't past half of its expected life. An amazing car.
2010 RX 350 Highlights
Base MSRP Excludes Destination Fee | $37,625 |
---|---|
Engine Type | Gas |
Combined MPG | 21 MPG |
Cost to Drive | $225/month |
Seating | 5 seats |
Cargo Capacity All Seats In Place | 40.0 cu.ft. |
front wheel drive | |
Warranty | 4 years / 50,000 miles |
Safety
Key safety features on the RX 350 include:
- Alarm
- Tire Pressure Warning
- Stability Control
- Post-collision safety system
NHTSA Overall Rating
The National Highway Transportation Safety Administration offers independent analysis.
- Frontal Barrier Crash RatingOverallNot RatedDriver5 / 5Passenger5 / 5
- Side Crash RatingOverallNot Rated
- Side Barrier RatingOverallNot RatedDriver5 / 5Passenger5 / 5
- Combined Side Barrier & Pole RatingsFront SeatNot RatedBack SeatNot Rated
- RolloverRollover4 / 5Dynamic Test ResultNo TipRisk Of RolloverNot Rated
IIHS Rating
The Insurance Institute of Highway Safety uses extensive crash tests to determine car safety.
- Small Overlap Front Driver-Side TestNot Tested
- Small Overlap Front Passenger-Side TestNot Tested
- Moderate Overlap Front Test – OriginalGood
- Moderate Overlap Front Test – UpdatedNot Tested
- Side Impact Test – OriginalGood
- Side Impact Test – UpdatedNot Tested
- Roof Strength TestGood
- Rear Crash Protection / Head RestraintGood
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