2006 Mercedes-Benz E-Class Review
Price Estimate: $812 - $1,306





+69
Mercedes-Benz E-Class model years
Edmunds' Expert Review
by the Edmunds Experts
Pros
- Sleek and dignified design inside and out, pleasing blend of ride and handling, sophisticated safety features, all-wheel drive available on both sedan and wagon models.
Cons
- More expensive than competitors, confusing control layout, electronically controlled brakes lack progressive feel.
What’s new
The base E320 is replaced with the E350 for 2006. The new model name indicates a new engine -- a 3.5-liter V6 with 268 hp, a 20-percent increase from the previous E320.
Edmunds says
Although it costs more than its peers, a combination of excellent driving dynamics, numerous safety and luxury features and high style make the 2006 Mercedes-Benz E-Class one of our favorites.
For sale near Lexington, MA
101 listings
- $5,999good price$1,297 below market
- 113,800 miles
- No accidents, 4 owners, personal use only
- 6cyl automatic
- Volare Motors (47 mi away)
- AWD/4WD
- Leather Seats
- Power Driver Seat
- Tire Pressure Warnin...
- Multi-Zone Climate C...
Close
Located in Cranston, RI
2006 Mercedes Benz E350 4Matic. 113,800 well serviced miles. Have both factory keys. Heated leather seats, am fm stereo, power moon roof, rear power s...
AutoCheck Vehicle History Summary
Accident Free Vehicle: Yes
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
19 Combined MPG (16 City/23 Highway)
Listing Information:
VIN: WDBUF87J46X186055
Stock: M-0883
Certified Pre-Owned: No
Listed since: 03-13-2025 - 300,000 miles
- 2 accidents, 4 owners, personal use only
- 8cyl automatic
- Eazy Auto (74 mi away)
- AWD/4WD
- Leather Seats
- Third-row seating
- Power Driver Seat
- Tire Pressure Warnin...
Close
Located in Taftville, CT
AutoCheck Vehicle History Summary
Accident Free Vehicle: No
Personal Use Only: Yes
History Provider: AutoCheck
Title Details: Clean Title
Salvage Vehicle: No
Frame Damage: No
Theft History: No
Lemon Status: No
Free History Report: No
Features and Specs:
16 Combined MPG (14 City/18 Highway)
Listing Information:
VIN: WDBUH83J56X189451
Stock: 189451
Certified Pre-Owned: No
Listed since: 08-02-2024
Vehicle overview
The E-Class has long been a staple of Mercedes-Benz lineup. Although the current car traces its lineage back to 1953 when the Pontoon model was introduced, the term "E-Class" essentially debuted along with the new-for-1986 300E (prior to that, the "E" in various Benz models stood for "Einspritzung," German for "fuel injection").
That somber sedan, propelled by either a gasoline or turbodiesel inline six, quickly developed a reputation for athletic performance and impeccable solidity. Initially, buyers could choose between a sedan and wagon, later on a coupe and convertible were added to the mix. Eventually, a V8 version of the sedan came on line in an attempt to fend off the onslaught of premium-quality and aggressively priced Lexus and Infiniti models. Catering to all needs and wants, an all-wheel-drive version, called the "4Matic," became available, as did the "wolf-in-sheep's-clothing" 500E sedan.
In 1994, Mercedes moved the letters to the front of the numbers to indicate the model series; hence the 300E became the E320. The next generation of the Mercedes-Benz E-Class debuted for 1996 with its eyes wide open. The big, oval headlights took some getting used to, but evidently, luxury car buyers quickly warmed up to the new E, as it was the top-selling car for the company. Once again, six, eight and turbodiesel versions were offered, though the oil burner was discontinued for 2000. Fortunately, the fully redesigned 2003 E-Class sedan didn't stray too far from the previous iteration. Exterior styling isn't dramatically different; the headlamps, though, are sleeker and blend into the body more elegantly than in the past. Overall, the car gives off a sportier image than the sedate outgoing model without losing its elegant demeanor.
For 2004, the E-Class wagons got a fresh start as well, picking up the sleeker bodywork and all of the engineering refinements. Noting increased consumer interest in luxury wagons, Mercedes is offering both V6 and V8 versions this time around. The 4Matic all-wheel-drive system is available as well, and those living in cold climates, should take note that they can now get it on the sedan as well. For 2005 the diesel Benz returned in the E320 CDI model. CDI stands for Common-rail Direct Injection, and this turbodiesel six is notable for its strong performance, excellent fuel mileage and exceptionally quiet and refined operation.
For 2006, the E320 is replaced with the E350, which features a larger V6 with 20-percent more horsepower. One thing that hasn't changed is the high price of admission, as the 2006 Mercedes-Benz E-Class sedans and wagons remain some of the most expensive midsize luxury cars on the market. That said, these are also some of the most capable, most luxurious and safest cars on the road. If you have plenty of money and you're shopping for a luxury car, your local Mercedes-Benz dealership would be a good place to start.
Performance & mpg
The E350 comes with a 3.5-liter V6 rated at 268 horsepower and 258 pound-feet of torque. The diesel engine in the E320 CDI is a 3.2-liter with 201 hp, an impressive 369 lb-ft of torque and a 27 city/37 highway EPA rating. The E500 and its 5.0-liter V8 pump out 302 hp and 339 lb-ft of torque. A five-speed automanual transmission is fitted to each, except the rear-drive E350 and E500, which feature a seven-speed unit. The 4Matic all-wheel-drive system is optional.
Safety
In addition to expected features like stability control and head- and torso-protecting side airbags, the Mercedes-Benz E-Class boasts electronic braking. This system provides a more precise interface between the brakes and other active safety systems. Stopping distances are convincingly short, but the brakes can't match the progressive feel of conventional setups. In government crash tests, the E-Class earned four stars (out of five) for frontal impacts and a perfect five stars for side impacts. In IIHS frontal offset crash testing, the midsize Benz was named a "Best Pick" in its class.
Driving
The new V6 is a refined unit with plenty of power for most any situation. The 45 state-certified E320 CDI offers outstanding fuel economy with no sacrifice in acceleration compared to the E350. Money no object, the smooth and silent 5.0-liter V8 is also a great choice. All E-Class cars demonstrate exemplary road manners with a comfortable, controlled ride. Although the 2006 Mercedes-Benz E-Class isn't as athletic as BMW's 5 Series, those who like to take the back roads will not be disappointed by the car's grip and response around turns.
Interior
The well-appointed cabin features a two-tone dash with wood accents, top-grade materials and nicely dampened controls. One of the most extravagant options is the Drive Dynamic front seats, which not only adapt for comfort but automatically provide additional lateral support during cornering. Two adults can easily fit in the backseat, but larger occupants may find thigh support and foot room in short supply.
2006 Mercedes-Benz E-Class models
The Mercedes-Benz E-Class is available in both sedan and wagon form in one of three trim levels -- E350, E320 CDI and E500. The E350 and E500 can be had in either body style; the E320 CDI is a sedan only. Standard features on the E350 and E320 CDI include leather upholstery, wood interior trim, 10-way power seats and dual-zone climate control. E500 models add 17-inch wheels, an adaptive suspension, four-zone climate control and an upgraded Bose sound system. A number of high-tech options are available, including the Keyless Go system, self-adjusting active ventilated seats and adaptive cruise control.
Compare 2006 Mercedes-Benz E-Class trim levels
Helpful trims summary and side-by-side comparison chart

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Cost to DriveCost to drive estimates for the 2006 Mercedes-Benz E-Class E350 4dr Sedan (3.5L 6cyl 7A) and comparison vehicles are based on 15,000 miles per year (with a mix of 55% city and 45% highway driving) and energy estimates of $3.91 per gallon for premium unleaded in Massachusetts.
Monthly estimates based on costs in Massachusetts
$237/mo for E-Class E350
E-Class E350
vs
$161/mo
Avg. Midsize Car
See Edmunds pricing data
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Mercedes-Benz E-Class Reviews
Owner Reviews
5(78%)
4(14%)
3(6%)
2(2%)
1(0%)
Most Helpful Owner Reviews
Trending topics
+600k Miles and Still Going STRONG
5 out of 5 starsChristian Hans Koerner, 12/07/2018
2006 Mercedes-Benz E-Class E320 CDI 4dr Sedan (3.2L 6cyl Turbodiesel 5A)
Diesel Mercedes ARE the Cheapest Cars on the ROAD ! Period. I've retained all receipts, fuel ( +$60,000 in 10 years, average 70,000 per yr) Maintenance, etc. Cost per mile is lowest of any car I've driven, from VW Jetta Diesel, Jeep GC, Tahoe's, Camry, etc. Recently replaced ORIGINAL Turbo and Starter. Engine, knock on wood, has never been opened, Tranny rebuilt at 400,000 because I … drive like a German. The only thing I would change is the TAXES on Diesel. Since I burn LESS FUEL, Why does the Federal Govt and State charge me more, don't they want us Commoners to use LESS FUEL ?!?!?!
Love this car
5 out of 5 starssrsmartin, 08/26/2010
2006 Mercedes-Benz E-Class E320 CDI 4dr Sedan (3.2L 6cyl Turbodiesel 5A)
This car's average mileage for its first 51,000 miles is 30,6. On the highway I get 41+ at 70 mph. Add Mercedes legendary comfort and handling and this is a great car. I bought it used in 2009 from a dealer with a full MB warranty for $28 k. I'll never buy a new one again! It is my fourth Benz/first diesel, and I am now a diesel convert. Why drive anything else?
Oil pump problems
3.38 out of 5 starsHans, 08/20/2010
2006 Mercedes-Benz E-Class E350 4dr Sedan (3.5L 6cyl 7A)
Listen in the morning at start up for a whining noise. it is the oil Pump because very few mechanics change the front of the trans oil, there are two oil plug for the transmission. Mercedes will replace the oil pump even the vehicle is out of warranty because they know there is a problem . 06 and 07 E350 .
Mercedes does NOT stand behind their products
3 out of 5 starsdavid suazo, 10/25/2016
2006 Mercedes-Benz E-Class E350 4dr Sedan (3.5L 6cyl 7A)
Its a great car but this year model has too many problems. Mercedes does not stand behind their cars. I had to replace the balance shaft which cost me $4,500 because Mercedes made a design flaw. They eventually had a class action law suite succeed but they refused to fix my car. There was also a recall on the brake pump , again they refused to honor the recall saying they could not get … the correct code. 1 year later I had a catastrophic brake failure on the high way. Again they refused to fix it even though there was a recall. I called Mercedes headquarters in New Jersey, they again refused to honor there recall. I am very disappointed in Mercedes Benz, it appears all they want is your money but do not stand behind there products.
2006 E-Class Highlights
Sedan
E350
Base MSRP Excludes Destination Fee | $50,050 |
---|---|
Engine Type | Gas |
Combined MPG | 20 MPG |
Cost to Drive | $237/month |
Seating | 5 seats |
Cargo Capacity All Seats In Place | 15.9 cu.ft. |
Drivetrain | rear wheel drive |
Warranty | 4 years / 50,000 miles |
Safety
Key safety features on the E-Class include:
- Alarm
- Tire Pressure Warning
- Stability Control
NHTSA Overall Rating
The National Highway Transportation Safety Administration offers independent analysis.
- Frontal Barrier Crash RatingOverallNot RatedDriver4 / 5Passenger4 / 5
- Side Crash RatingOverallNot Rated
- Side Barrier RatingOverallNot RatedDriver5 / 5Passenger5 / 5
- Combined Side Barrier & Pole RatingsFront SeatNot RatedBack SeatNot Rated
- RolloverRollover5 / 5Dynamic Test ResultNo TipRisk Of RolloverNot Rated
IIHS Rating
The Insurance Institute of Highway Safety uses extensive crash tests to determine car safety.
- Small Overlap Front Driver-Side TestNot Tested
- Small Overlap Front Passenger-Side TestNot Tested
- Moderate Overlap Front Test – OriginalGood
- Moderate Overlap Front Test – UpdatedNot Tested
- Side Impact Test – OriginalNot Tested
- Side Impact Test – UpdatedNot Tested
- Roof Strength TestNot Tested
- Rear Crash Protection / Head RestraintGood
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